Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Flushing
ADR ID BADD_A01671
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.025      Flushing
23      Skin and subcutaneous tissue disorders
23.06      Skin vascular abnormalities
23.06.05      Skin vasomotor conditions
23.06.05.003      Flushing
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.01      Peripheral vascular disorders NEC
24.03.01.002      Flushing
Description A disorder characterized by episodic reddening of the skin, especially face, neck, or chest. [CTCAE] A transient reddening of the face that may be due to fever, certain drugs, exertion, or stress. [MeSH]
MedDRA Code 10016825
MeSH ID D005483
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Facial flushing | Flushed | Flushed chest | Flushed face | Flushed skin | Flushing | Flushing of face | Generalised flushing | Gross flushing | Pallor and flushing | Skin flushed | Flushing aggravated | Generalized flushing | Flushings
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Adenylate cyclase type 1Q08828T63609
Pro-neuropeptide YP01303T51671
Sodium/potassium-transporting ATPase subunit alpha-1P05023T40800
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00330Cabozantinib--
BADD_D00335Calcitonin--
BADD_D00336Calcitonin (salmon)--
BADD_D00344Canagliflozin--
BADD_D00347Candesartan cilexetil--
BADD_D00349Capecitabine--
BADD_D00354Captopril--
BADD_D00355Carbachol--
BADD_D00356Carbamazepine--
BADD_D00359Carbidopa--
BADD_D00364Carboplatin0.031170%
BADD_D00365Carboprost--
BADD_D00366Carboprost tromethamine--
BADD_D00367Carfilzomib--
BADD_D00370Carisoprodol--
BADD_D00371Carmustine--
BADD_D00374Carvedilol0.000197%
BADD_D00376Caspofungin--
BADD_D00377Caspofungin acetate--
BADD_D00382Cefazolin0.000745%
BADD_D00393Cefoxitin--
BADD_D00394Cefoxitin sodium--
BADD_D00399Ceftazidime--
BADD_D00405Ceftriaxone--
BADD_D00406Ceftriaxone sodium--
BADD_D00407Cefuroxime0.003512%
BADD_D00410Celecoxib0.002297%
BADD_D00412Cephalexin0.000077%
BADD_D00415Cerivastatin--
BADD_D00417Cetirizine0.000265%
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